ExoPRISM Exosome Extraction Kit is suitable for plasma and serum

Product Description

Extracellular vesicles (EVs) are membrane vesicles secreted by various cells, which participate in intercellular communication by transferring substances such as proteins, metabolites, and nucleic acids. A key consideration in the clinical development of EVs is the selection of traditional EV separation methods. Supercentrifugation requires a long time and a lot of effort, even for large-scale research and inexperienced researchers, but they prefer a fast and efficient way to separate EVs and obtain the desired yield and appropriate particle size. Therefore, a method that can quickly separate high-yield EVs will greatly promote such applications.

Extracellular vesicles (EVs) are membrane vesicles secreted by various cells, which participate in intercellular communication by transferring substances such as proteins, metabolites, and nucleic acids. A key consideration in the clinical development of EVs is the selection of traditional EV separation methods. Supercentrifugation requires a long time and a lot of effort, even for large-scale research and inexperienced researchers, but they prefer a fast and efficient way to separate EVs and obtain the desired yield and appropriate particle size. Therefore, a method that can quickly separate high-yield EVs will greatly promote such applications.

The ExoPRISM EV separation kit (suitable for plasma/serum) is a novel precipitation method that overcomes these obstacles by using low molecular weight electrolytes instead of PEG polymers. (i) EV samples separated and enriched by ExoPRISM are free of polymer contaminants. (ii) Due to the rapid reaction of our reagents and samples within 10 minutes, the overall processing time has been greatly reduced. (iii) ExoPRISM "reagent can be easily removed from enriched EVs and can be eluted with the buffer solution of your choice. (iv) Therefore, ExoPRISM 'has no impact on downstream analysis or application. The main protein pollutants, such as albumin and fibrinogen, are effectively removed during the operation process.

ExoPRISM EV Extraction Kit (applicable to plasma&serum)

This kit includes two reagents: reagent P and reagent Q, which have been optimized for plasma and serum samples, respectively. Reagent P is the EV precipitation solution, and reagent Q is the washing solution

Ingredient List

Usage method

The volume of required reagents is calculated based on 1 ml of sample (body fluid). When using more samples (body fluids), please increase the amount of reagents.

ExoPRISMExtracellular vesicle extraction kit