SpectraMax Paradigm Cartridge Multifunctional ELISA reader

A multifunctional microporous reading machine based on grating type and filter, a cost-effective instrument that can also obtain high-quality experimental results. Can detect light absorption, fluorescence, chemiluminescence, fluorescence polarization, time-resolved fluorescence, upconversion luminescence TR-FRET， The detection modes include endpoint method, dynamic method, linear and area scanning method, and support 6-1536 well plates.

A high-throughput, user upgradable multifunctional microplate detection platform that can easily perform functional upgrades within two minutes. Can detect light absorption, fluorescence, chemiluminescence, fluorescence resonance energy transfer, time-resolved fluorescence, fluorescence polarization, upconversion luminescence, TR-FRET, HTRF, AlphaScreen, Western Blot, etc., supporting 6-3456 well plate detection.

SpectraMax ® Paradigm ® The multifunctional detection platform adopts a patented card module design, allowing users to add, combine, and replace detection modules in real-time within two minutes. The modular concept of this enzyme-linked immunosorbent assay (ELISA) not only ensures various universal detection applications, but also provides the possibility to expand the constantly increasing and rapidly changing new special applications. Therefore, your application requirements can constantly change, but your machine does not need to be replaced. All you need to do is add a small detection card box, and everything will be solved easily.

main features

Card box design, user end, future upgradable

High throughput (6-3456 holes), multi-channel (simultaneous single excitation/dual emission, dual excitation/dual emission)

● Top and bottom automatic Z-axis height optimization function

● Dual color Western Blot detection

Customized special testing card box service

application area

Utilizing the UV light absorption region for quantitative and purity rapid detection of DNA, RNA, and proteins, PicoGreen/NanoOrange/Bradford rapid detection, ELISAs/enzymatic kinetics detection, drug degradation experiments, cell viability, cytotoxicity, cell proliferation detection, Caspase-3/7 and various apoptosis markers detection and protease detection, CatchPoint cAMP/cGMP detection, receptor ligand binding, SNP genotyping, drug target research, tryptophan self fluorescence detection, green fluorescent protein detection, reporter gene detection, ADME Tox experiment, fluorescence based cell migration, kinase and ATPase detection, bioluminescence fluorescence resonance energy transfer (BRET), Multi Tox cell viability analysis, HTRF detection, AlphaScreen detection, Western Blot detection experiments based on time-resolved fluorescence, etc.

Experimental examples

It is known that inflammation is the body's response to infection, stimulation, or other harm, accompanied by the production of endothelial cell chemokines and the expression of adhesion molecules, which can lead to a large infiltration of neutrophils. The discovery of new anti-inflammatory drugs can have a negative regulatory effect on these factors, reduce tissue damage, and improve therapeutic efficacy. Screening these therapeutic drugs requires a rapid and sensitive cytokine quantitative detection platform. SpectraMax Paradigm is a freely upgradable platform that, combined with AlphaLISA, provides a powerful screening tool for discovering new treatment options in pathology related endothelial cell models. The sensitivity and speed of up to 1536 well microplate detection capability, combined with pre optimized software solutions, allow users to perform faster and more efficient detection.