Swiss Ceido online cell analyzer

Herner supply, direct procurement from German headquartersSwiss Ceido online cell analyzer, Near30Years of experience in importing industrial products, original products, supporting selection, providing you with one-on-one solutions: stable delivery time, competitive pricing, with a presence in China8The large office provides relevant after-sales services.

Company Profile

SwitzerlandCeidosThe company is a company dedicated to the research and development of online monitoring technology for biological processes. The company is committed to providing real-time and automated cell culture analysis solutions for research and production in the fields of biopharmaceuticals and cell therapy. The technology developed aims to help users optimize their process flow by reducing manual intervention and providing continuous process data.

Product Type

CeidosThe products provided mainly revolve around online monitoring of cell culture processes, with core product types including:

1. Online cell viability and density analyzer

2. Integrated Cell Culture Process Monitoring System

3. Single use sterile microfluidic detection kit

4. Cell culture data analysis and management software

5. Bioreactor Integration Kit

Main models

The main equipment and supporting models of this brand include:

1. C-Netics 100Basic model of online monitoring device.

2. C-Netics ProProfessional model of online monitoring instrument.

3. Cartridge-SA sterile testing kit suitable for a certain range of cell densities.

4. Software-BaseBasic data analysis and management software.

5. Kit-Integration-SSystem integration kit.

Swiss Ceido online cell analyzerProduct Introduction

Core products:C-NeticsSeries online cell analyzer
C-NeticsThe series isCeidosThe core product is used to connect bioreactors and achieve automatic and online measurement of cell density and viability during the cultivation process.

·Product OverviewThe system consists of a reusable analyzer host and a matching single use, pre sterilized microfluidic detection box. The host controls the automatic sampling and analysis process, and users can view the results in real time through the software. The analyzed samples can be returned to the bioreactor or discarded as needed.

·Technical Specifications：

otesting indicatorsCell density and cell viability.

oTesting ScopeThe cell density is approximately0.5x10^6to2x10^7cells/mL(Specifically affected by cell type and detection kit); The cell viability is approximately15%to100%.

omeasure frequencyUsers can customize configurations and support multiple measurements per hour.

oConnection compatibilityCan be connected to common bioreactor sampling ports through adapters.

·working principleWhen the system is working, connect the sterile detection box to the bioreactor flow path and insert it into the host.

1. Cell density detectionThe built-in microscope of the host automatically images the cells passing through the detection box, and calculates the number of cells per unit volume through image analysis algorithms to obtain density values.

2. Cell viability detectionThe microelectrodes inside the detection box apply a specific frequency of electric field to generate dielectrophoresis force. Due to the different electrical properties of live and dead cells, their movement speed in an electric field will vary. The host tracks the movement speed of cells through machine vision technology, distinguishes and calculates the proportion of live cells based on this, and calculates the viability.

Advantages and Features

1. Online automation operationThe system can be directly integrated into a bioreactor, automatically completing sampling and measurement according to settings during the cultivation process, greatly reducing the need for manual sampling and offline analysis.

2. Closed aseptic testingAdopting a pre sterilized single use detection kit and completing analysis in a closed pipeline, the sample can be returned to the reactor, which helps maintain the sterile state of the culture system and reduce the risk of contamination.

3. Dual method combination analysisSimultaneously using optical microscopy imaging and cell motion analysis based on dielectrophoresis to obtain cell density and viability data.

4. Provide process trend dataCapable of continuous and frequent measurement, recording the complete trend of cell growth and state changes, providing data support for process research and problem troubleshooting.

Main applications

C-NeticsThe system is suitable for various fields that require real-time understanding of suspended cell culture status, mainly including:

1. Biopharmaceutical production: Used for monitoringCHOTheHEK293The state of mammalian cells during the production of monoclonal antibodies, recombinant proteins, or vaccines.

2. Cell and gene therapy(CGT): Used forCAR-TProcess development, optimization, and production monitoring of therapeutic cell products such as cells and stem cells.

3. Biotechnology developmentProvide real-time cell status feedback in research and development such as medium screening and process parameter optimization.

4. Pilot scale studyProvide online monitoring methods that are consistent with the production scale during the process of process scaling up.

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