Sonitron Ultrasonic Transfection Device

NegotiableUpdate on 03/07

Model

Nature of the Manufacturer: Producers

Product Category

Place of Origin

Online Consult

Overview

After nearly 30 years of development and innovation, acoustic perforation has become an indispensable technical means in the field of gene functional research. As the exclusive agent in China, Huayuexing Instrument Co., Ltd. recommends NEPA GENE's instruments from Japan to you

Product Details

Sonitron GTSThe ultrasonic transfection instrument adopts the principle of ultrasonic waves, which is safe, reliable, flexible, and efficient. Suitable for gene transfection in clinical trial research(gene transfection)And drug transport(drug delivery)Domain.

Main features:

Safety: Because ultrasound can be applied in clinical practice, the instrument uses the principle of ultrasound transfection to ensure the safety of later clinical trial research.
Flexibility: The sensor module of the ultrasonic transfection instrument has self calibration function and can be replaced.
Can be used for focused ultrasound research (FUS): with a high-intensity focused ultrasound sensor module.
Can be used in conjunction with microbubbles: The instrument can be used in conjunction with microbubbles to improve transfection efficiency; And special microbubbles (such as Targesphere SA) can be used to target specific cells.

Application scope:

Suitable for in vitro transfection of animal cells, as well as in vivo transfection in animals (including in the uterus or ovaries, etc.).

Primary cells and cell lines, such as HFLS-RA, Hela, KATO Ⅲ, MKN-45, CHO, NIH/3T3, HL-60, C1271, T24, Mouse ascites, Rat bladder, PC3, U937, etc.
Mouse's brain, lungs, liver, kidneys, spleen, blood vessels, spinal cord, skin, gingiva, peritoneum, joints, foot pads, ears, etc.
The brain, lungs, heart, liver, intestine, amniotic membrane, etc. of mouse embryos.
The small intestine, large intestine, salivary glands, retina, and cornea of rats.
The retina, cornea, etc. of a rabbit.
The brain of bees, etc.
African clawed toad (Xenopus).
Silkworm's blood cells, silk glands, midgut, fat pad, martensitic ducts, ovaries, testes, etc.

Technical parameters:

Frequency	Plane Wave Transducers: 1MHz HIFU Transducers: 2.2MHz, 3.5MHz Available range: 800k - 8MHz
Ultrasound Intensity	Plane Wave Transducers: 0.01-0.5W/cm²or 0.1-5W/cm² HIFU Transducers: 10-200W/cm²or 100-2000W/cm²
Duty Cycle	On: 1～20, Off: 0～20, msec or sec
Treatment time	0-20 min
Preset	18 preset conditions
Power source	Setting 1 (default): 100V/50Hz, 110V/60Hz, Setting 2: 230V/50Hz
Dimensions, Weight	310W x 230D x 140H mm, 5kg

reference:

Suppression of tumor growth by intra-muscular transfer of naked DNA encoding adrenomedullin antagonist.Cancer Gene Therapy, Volume 14, Number 1, Pages 39-44, January 2007.
Local delivery system of cytotoxic agents to tumors by focused sonoporation.Cancer Gene Therapy, Volume 14, Number 4, Pages 354-63, April 2007.
In Vitro Development of Cloned Embryos Derived from Miniature Pig Somatic Cells after Activation by Ultrasound Stimulation.Cloning Stem Cells, Volume 8, Number 3, Pages 159-165, September 2006.
Antitumor effect of TNP-470, an angiogenesis inhibitor, combined with ultrasoundirradiation for human uterine sarcoma xenografts evaluated using contrast color Doppler ultrasound.Cancer Science, Volume 98, Issue 6, Page 929-935, June 2007.
Production of NAADP and its role in Ca2+ mobilization associated with lysosomesin coronary arterial myocytes.American Journal of Physiology - Heart and Circulatory Physiology, Volume 293, Issue 1, Pages H274-H282, July 2006.

More information can be logged inhttp://www.nepagene.jp/E/Eindex.htm

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