Applicability of oral liquid disperser in the production process
Oral liquid disperserAdopting a split structure, the speed can reach up to 14000 rpm, which is 4-5 times that of a regular disperser. It has outstanding applications in the preparation of pharmaceutical suspensions and lotion, such as oral liquid, albendazim suspension, and Baoxime suspension. The particle size can generally be refined to DN90 ≤ 10 μ m.Oral liquid disperserIt has the advantages of small dosage, fast absorption, stable quality, convenient carrying and taking, and easy storage, especially suitable for industrial production. Some varieties are suitable for emergency medication in traditional Chinese medicine, such as Sini Tang oral liquid and Yinhuang oral liquid. Therefore, in recent years, tablets, traditional Chinese medicine mixtures, injections, etc. have been modified into oral liquids, making them one of the rapidly developing dosage forms in pharmaceutical preparations. However, the production equipment and process conditions for oral liquids require high standards and are relatively expensive.
Oral liquids are all used orally, so the requirements for oral liquid dispersers are very high, and the core is quality and safety. The quality of oral liquid depends on the refinement of particle size. The smaller the particle size of the material, the more stable the product is and less likely to precipitate, and it is easier for the human body to absorb. The oral liquid disperser is mainly composed of three layers of dispersing heads. During operation, the material enters the dispersing chamber through the feeding port and first reaches the dispersing head for processing. Due to the high-speed operation of the rotor teeth by the motor, eddy currents and centrifugal force effects are generated, causing the material to be axially sucked into the dispersing head. Then it is high-speed pressed out along the gap between the stator and rotor to complete the first shearing action. Afterwards, in the strong shearing gap between the rotor teeth and stator teeth, the material is strongly torn and flows out from the gap of the stator teeth to complete the second shearing action. Then, the flowing material enters the second layer dispersing head chamber, and the processed material is sheared again (the principle is the same as above), ensuring that the mixing and dispersion obtain a very narrow particle size distribution and obtain smaller droplets and particles. The generated mixture has better stability, Meet the particle size requirements for vaccine production.
Oral liquid disperser is more convenient for production employees to operate. After the materials are put into the feeding port, they are automatically discharged from the discharging port. If there is a stable process route, it can be directly connected to the previous process through pipelinesOral liquid disperserIt can achieve unmanned operation and is applicable in the production process. The design of the oral liquid disperser meets the requirements of the pharmaceutical industry and also meets the particle size requirements of different products. It has great prospects for application in the dispersion and mixing process of pharmaceuticals.